Active Clinical Trials

Clinical trials are at the heart of our work to bring innovative medicines to people with a particular disease or condition. Learn more about the active studies conducted by Novartis including opportunities to get involved.

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Study title Condition Phase Location

Study Assessing the Efficacy, Safety and PK of Alpelisib (BYL719) in Pediatric and Adult Patients With PIK3CA-related Overgrowth Spectrum

 		PIK3CA-related Overgrowth Spectrum (PROS) Phase2

The Belgian REAL (BE.REAL) Registry

 		Atherosclerotic Cardiovascular Disease

Phase 3 Study to Evaluate Two Regimens of Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS-SLE 1)

 		Systemic Lupus Erythematosus Phase3

Long-term Safety, Tolerability and Effectiveness Study of Ofatumumab in Patients With Relapsing MS

 		Relapsing Multiple Sclerosis Phase3

A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis

 		Aortic Stenosis Phase2

Roll-over Study to Allow Continued Access to Ribociclib

 		Metastatic Breast Cancer Phase4

Effectiveness of Brolucizumab in Pre-treated Patients With nAMD in the Real-world Setting

 		Neovascular Age-related Macular Degeneration

Study to Assess the Safety of Alpelisib Plus Fulvestrant, in Men and Post-menopausal Women With HR-positive, HER2-negative, Advanced Breast Cancer (aBC) With PIK3CA Mutation, Whose Disease Progressed on or After Endocrine Treatment

 		Advanced Breast Cancer Phase4

A Study of Secukinumab to Evaluate Maintenance of Response in Participants With Non-radiographic Axial Spondyloarthritis Who Achieved Remission

 		Non-radiographic Axial Spondyloarthritis Phase4

A Study of Ianalumab (VAY736) in Patients With Primary Immune Thrombocytopenia (ITP) Previously Treated With at Least Two Lines of Therapies

 		Primary Immune Thrombocytopenia (ITP) Phase2